About The Committee

The major purpose of the CPG Committee of the CSN is to develop CPGs or Clinical Practice Recommendations for CSN members. The overriding goal is to improve the delivery of health care to kidney disease patients in Canada.

Clinical practice guidelines (CPG) are systematically developed statements to assist practitioners and patients reach appropriate health care decisions. Their purpose is "to make explicit recommendations with a definite intent to influence what clinicians do." If developed properly, CPG assimilate and translate the abundance of evidence published on a daily basis into practice guidelines or recommendations.

In doing so, CPGs aim to reduce the use of unnecessary or harmful interventions, and facilitate the treatment of patients to achieve maximum benefit and minimum risk at an acceptable cost. CPGs are not meant to replace sound medical decision making which takes into account critical elements relevant to patient care including patient preferences and clinician experience.

Terms of Reference

CKD

PERITONEAL DIALYSIS

HEMODIALYSIS

ANEMIA

TRANSPLANT

CSN Reports & Position Papers

HEMODIALYSIS

KDIGO Clinical Practice Guidelines

CKD

TRANSPLANT

Other Canadian Clinical Practice Guideline Groups

Documents related to clinical practice guideline development

External Links

Committee Members

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Dr. Tyrone
Harrison

Chair, CPG Committee

Dr. Tyrone Harrison
Chair, Clinical Practice Guidelines Committee

Dr Tyrone Harrison MD PhD is an assistant professor of Medicine at the University of Calgary, where he works as a health services researcher and nephrologist. His current research program is mainly focused on integrating person-centredness within risk prediction strategies and population-based cohort studies for people with chronic diseases. His work is funded by the Kidney Foundation of Canada, and he is currently supported by a KRESCENT New Investigator Award (2023-2026). He is the current Chair of the CSN clinical practice guidelines committee. As part of the guidelines committee work, he has interest in incorporating the perspectives of people with lived experience and other stakeholders in determining committee priorities.

Dr. Harrison's Bio
Lisa-Miller

Dr. Lisa
Miller

Vice-Chair, CPG Committee

Dr. Lisa Miller

Dr. Lisa Miller received her MD at Memorial University of NL, then completed her internal medicine and nephrology training at Queens’s University.  She is currently an Assistant Professor at the University of Manitoba and a clinical nephrologist with Shared Health Manitoba.  Dr. Miller is an active member in the Canadian Society of Nephrology,  previously co-leading the development of the CSN Vascular Access Curriculum.  She is currently an active member of the CSN Guidelines Committee and leading the Choosing Wisely Canada Nephrology update.  Her clinical and research interests include vascular access, hemodialysis outcomes, and quality improvement in chronic kidney disease and hemodialysis.  She is involved with multiple patient care and advocacy committees, including core member of the Conservative Kidney Management Committee.  She is also currently pursuing further healthcare leadership training including recent completion of the University of Toronto Healthcare Leadership program. 

Dr. Miller's BIO
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Dr. Anna
Mathew

Past-Chair, CPG Committee

Dr. Anna Mathew
Past-Chair, Clinical Practice Guidelines Committee

Associate Professor, Division of Nephrology, Department of Medicine
Staff Nephrologist, St. Joseph Healthcare Hamilton

Dr. Anna Mathew completed medical school at University of Toronto, and residency and nephrology fellowship at Western University. She then completed an MPH (Quantitative Methods) at Harvard University.  Dr. Mathew is Associate Professor of Medicine at McMaster University and a staff nephrologist at St. Joseph’s HealthCare Hamilton, where she is Medical Director of hemodialysis.  Her clinical interests include chronic kidney disease, resistant or secondary hypertension, and obstetrical nephrology.  She serves in leadership and advisory roles at the regional and provincial level, focusing on public policy and quality improvement in the areas of hypertension, hemodialysis, and pregnancy in women with kidney disease.

Dr. Mathew's Bio
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Dr. Ahsan
Alam

Dr. Ahsan Alam

Dr. Ahsan Alam is an Associate Professor of Medicine at McGill University. He is a staff nephrologist and transplant nephrologist  with the multiorgan transplant program at the McGill University Health Centre (MUHC). He holds a Master's degree in Clinical Research from Tufts University in Boston and is a member of the Research Institute of the MUHC. Dr. Alam is involved in several clinical research studies and educational initiatives related to autosomal dominant polycystic kidney disease and is also a medical director of the living donor transplant program at the MUHC.

Dr. Alam's Bio
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Dr. Rahul
Chanchlani

Dr. Rahul Chanchlani

Dr. Rahul Chanchlani is an Associate Professor in the Division of Nephrology, Department of Pediatrics at McMaster Children’s Hospital. After finishing his initial medical training from India, he completed a clinical fellowship in pediatric nephrology at the Hospital for Sick Children, Toronto, and also pursued a Master's in Clinical Epidemiology and Clinician Investigator Program from the University of Toronto. He is an associate faculty in the Department of Health Research Methods, Evidence, and Impact (HEI), and cross-appointed as a Scientist at ICES and at the Population Health Research Institute (PHRI), McMaster University.  

Dr. Chanchlani is one of the 14 participants selected from 12 countries by the International Society of Nephrology for the Emerging Leader’s Program, which helps early-career nephrologists to become qualified for a leadership role in the advancement of global kidney care. In addition to clinical and teaching commitments, Dr. Chanchlani has an established research program that aims to promote interdisciplinary collaborations among peers and experts to address key knowledge gaps in common kidney diseases such as acute kidney injury, kidney transplantation, hypertension and nephrotic syndrome among children. As principal investigator, his research program is supported by grants from various local, provincial and national organizations including CIHR and Kidney Foundation of Canada. He has so far published >55 peer-reviewed papers and has supervised learners at all levels of training.

Dr. Chanchlani's Bio
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Dr. David
Clark

Dr. David Clark

Dr. David Clark is a nephrologist and Assistant Professor of Medicine at Dalhousie University in Halifax, Nova Scotia. He received his MD at the University of Ottawa and completed Internal Medicine and Nephrology residency training at Dalhousie University as well as a clinical fellowship in Home Dialysis and MSc of Clinical Epidemiology and Biostatistics at Western University. He is the current Medical Lead for the Halifax Home Dialysis & Percutaneous Peritoneal Dialysis Catheter Insertion Programs, as well as the Program Director for the Home Dialysis Fellowship Training Program. He conducts clinical research within his interest areas of home dialysis & interventional nephrology and is an active member of the Kidney Research Institute of Nova Scotia. He is also a member of the CSN Scientific and Clinical Practice Guidelines Committees. 

Dr. Clark's Bio
Gregory-Hundemer

Dr. Gregory
Hundemer

Dr. Gregory Hundemer

Dr. Hundemer is an Assistant Professor of Medicine with a cross appointment at the School of Epidemiology and Public Health at the University of Ottawa, an Associate Scientist at the Ottawa Hospital Research Institute, and a Staff Nephrologist at the Ottawa Hospital. He received his MD from Vanderbilt University (2007). Following a 4 year stint as a flight surgeon in the US Air Force, he completed his internship and residency at Massachusetts General Hospital (2015) followed by nephrology fellowship at the joint Brigham and Women’s Hospital/Massachusetts General Hospital program (2018). He was recruited to Ottawa in 2018. His clinical and research interests include secondary hypertension and chronic kidney disease. He is a current KRESCENT New Investigator awardee, and his research has been funded by the CIHR, NIH, and Kidney Foundation of Canada

Dr. Hundemer's Bio
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Dr. Phil
McFarlane

Dr. Phil McFarlane

Dr. Phil McFarlane is a clinical-investigator in the Division of Nephrology at St. Michael's Hospital in Toronto, and an assistant professor at the University of Toronto.  At St. Michael’s he is the Medical Director of Home Dialysis and the Chief Nephrologist in the Live Kidney Donor Program.  He is a member of the Diabetes Canada Clinical Practice Guidelines group, the Canadian Society of Nephrology guideline group, and the Hypertension Canada guideline group.  He has completed his Ph.D. in health economics at the Institute for Medical Sciences at the University of Toronto.  His areas of research interest include health economics and outcomes research.  He is currently the Ontario Renal Network Provincial Medical Lead for hemodialysis.  He has published over 100 peer-reviewed manuscripts and three book chapters.

Dr. McFarlane's Bio
Reem-Mustafa

Dr. Reem
Mustafa

Dr. Reem Mustafa

Dr. Mustafa is a clinical nephrologist who is board certified in Preventive Medicine, Internal Medicine and Nephrology. She is especially interested in managing patients with chronic kidney disease and their other medical conditions to slow the progression of their disease.

Dr. Mustafa is very interested and formally trained in research with a Master’s degree in Public Health and a PhD degree in Health Research Methodology/Clinical Epidemiology. Dr. Mustafa’s research interest focuses on the application of principles of evidence-based medicine in clinical and public health decision-making. She also studies the effect of these principles on clinical and patient-important outcomes. She is also interested in utilizing pragmatic clinical trials to study the effect of different feasible interventions to improve the outcomes and quality of life of patients with kidney disease. She is especially interested in decision-making regarding healthcare related tests and diagnostic strategies; challenges and suggested solutions, which included the use of models when direct evidence is lacking. She has extensive experience in the development and assessment of clinical practice guidelines through her work with The Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group and her role on the GRADE Guidance Group (Executive Committee). She has been involved with multiple guideline development groups internationally through the World Health Organization (WHO), the American Society of Hematology (ASH), American College of Physicians (ACP), The Infectious Disease Society of America (IDSA) among others. She is a co-founder of the U.S. GRADE network and the Evidence Foundation which mission is to support initiatives in evidence-based health care through training, mentorship, education, and collaboration with multiple stakeholders. She is especially interested in implementing conceptual frameworks for stakeholder engagement and methods for evaluating engagement for systematic reviews and guidelines development with a focus on engaging and empowering diverse and underserved populations.

Dr. Mustafa's Bio
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Dr. Annie-Claire
Nadeau-Fredette

Dr. Annie-Claire Nadeau-Fredette

Dr. Annie-Claire Nadeau-Fredette is a Clinical scientist and Associate Professor of Clinical Medicine at the Université de Montréal. She is the Director of Home Dialysis and a staff nephrologist at Hôpital Maisonneuve-Rosemont. Dr. Nadeau-Fredette received her MD (2007), completed a Masters in Clinical Research (2016) at the Université de Montréal and home dialysis research fellowships at the University of Toronto (2013) and University of Queensland (2015). Dr. Nadeau-Fredette is a FRQS Junior 1 research scholar, has >50 publications and is involved in national and international studies in chronic kidney disease and dialysis. Her research program focuses primarily on improving outcomes of transitional periods for patients with advanced chronic kidney disease and on home dialysis.

Dr. Nadeau-Fredette's Bio
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Dr. Gihad
Nesrallah

Dr. Gihad Nesrallah
Chair, Clinical Practice Guidelines Committee
Member, Methods Subcommittee

Dr. Nesrallah completed his medical training and nephrology fellowship at Western University, his MSc Health Research Methodology at McMaster University, and his MBA with the Kellogg-Schulich Executive program. His nephrology practice is based at Humber River Hospital in Toronto and he has faculty appointments at Western and the University of Toronto. His interests include observational epidemiology, quality improvement, and knowledge synthesis. He serves in various leadership and advisory roles in the public and private sectors in areas spanning data analytics, business strategy, quality improvement, and public policy. He is an avid chef and snowboarder, and a fortunate husband and father of 3 children.

Dr. Nesrallah's Bio
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Dr. Krista
Ryz

Dr. Krista Ryz

Dr. Krista Ryz is an Assistant Professor of Medicine at the University of Manitoba.  She is a staff nephrologist at St. Boniface General Hospital in Winnipeg, where she also spends a portion of her clinical time as an Interventional Nephrologist.  She serves as the Medical Coordinator of Renal Health Clinics for SBGH and in this role is working on projects to improve outcomes for patients with progressive CKD. She has interests in medical education and has appointments in both the Department of Medicine and Section of Nephrology in this capacity. 

Dr.Ryz's Bio
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Dr. Melissa
Schorr

Dr. Melissa Schorr

Dr. Schorr completed her Internal Medicine and Nephrology training at Western University. She is currently completing her Ph.D. in Health Research Methodology at McMaster and the Clinician Investigator Program at Western. Her research focus is Pragmatic Clinical Trials in patients on hemodialysis. She is dedicated to developing high-quality trials in this patient population to improve the evidence base on which clinical decisions are made, and, ultimately, to improve outcomes in our patients.

Dr. Schorr's Bio
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Dr. Michelle
Wong

Dr. Michelle Wong

Dr. Michelle Wong, MD, MSc, MPH, FRCPC, is a Clinical Assistant Professor in the Department of Medicine at the University of British Columbia, and a clinical researcher at BC Renal. She is also a 2021 cohort member of the International Society of Nephrology Emerging Leaders Program. Dr. Wong’s research has focused on complications of chronic kidney disease, including protein-energy wasting, anemia, volume overload, and hypertension. She has been involved in systematic reviews the World Hypertension League’s “Science of Sodium” initiative, as well as international cohort studies with the Dialysis Outcomes and Practice Patterns Study, and the Chronic Kidney Disease Outcomes and Practice Patterns Study. At BC Renal, she is currently leading an interprofessional research program in renal nutrition.

Dr.Wong's Bio
Somaya Zahran 2023

Dr. Somaya
Zahran

Dr. Somaya Zahran

It is a pleasure to join the CSN Clinical Practice Guidelines Committee as the first trainee member.

My name is Somaya, I am a PGY4 Nephrology at McGill University. I completed Med School in Egypt, then obtained my PhD from the University of Alberta before matching to Internal Medicine residency at McGill University. I served as an executive committee member for several student associations at the University of Alberta and was a VP academic then a chief medical resident for internal medicine at  McGill.

On a professional level, I hope to expand my knowledge of epidemiological research methods during my fellowship, and I aspire to become a clinician scientist practicing Transplant Nephrology. In my free time, I enjoy nature walks and baking.

I am honored to be part of the CSN community and hope to learn from and contribute to the guidelines committee.

Dr. Zahran's Bio
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